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Pediatric diffuse midline glioma arise in the brainstem (A, B) or thalamus (C, D). T2 weighted MR imaging (A, B, C) demonstrates a homogenous, expansile, infiltrative lesion with extension within white matter tracts. Minimal to heterogenous enhancement may be observed on T1 post-gadolinium sequences (D). Local mass effect and perilesional edema may also be seen.
