Figure 3.

Fate map of BDNF expression in sensory ganglia and spinal cord neurons A–E, In double transgenic BDNF-Cre/floxed-tdTomato mice, tdTomato (red) was recorded in a large number of DRG neurons, but not in macrophages, identified by expression of Iba1 (green in A, B). A wide variety of DRG neurons expressed tdTomato, some of which were marked by IB4 binding (blue in E). Insets B–D show high magnifications of cells from A. F–H, TdTomato (red) was also expressed in spinal cord neurons, but not in microglia (Iba1+, green in G) or astrocytes (GFAP+, green in H). Insets show high magnification of labeled cells. Scale bars = 100 μm.