Table 3.
Long-term outcomes in subgroups
| Variables | No. of Patients | No. of Events | Event Rate* (4-year) | Hazard Ratio (95% CI) | P-value | P-value for interaction |
|---|---|---|---|---|---|---|
| Outcome: Death | ||||||
| 3 Diseased Vessels | 0.03 | |||||
| EES | 166 | 29 | 26.30 | 1.60 [0.84, 3.05] | 0.15 | |
| CABG | 166 | 23 | 16.11 | Reference | ||
| 2 Diseased Vessels | ||||||
| EES | 300 | 46 | 23.11 | 0.67 [0.44, 1.03] | 0.07 | |
| CABG | 300 | 65 | 24.82 | Reference | ||
| Complete Revascularization | 0.52 | |||||
| EES | 211 | 33 | 19.01 | 0.88 [0.53, 1.45] | 0.61 | |
| CABG | 211 | 44 | 20.68 | Reference | ||
| Incomplete Revascularization | ||||||
| EES | 852 | 152 | 26.36 | 1.05 [0.81,1.36] | 0.69 | |
| CABG | 852 | 152 | 21.19 | Reference | ||
| Outcome: Myocardial Infarction | ||||||
| 3 Diseased Vessels | 0.07 | |||||
| EES | 166 | 14 | 11.89 | 6.00 [1.34, 26.81] | 0.02 | |
| CABG | 166 | 5 | 3.21 | Reference | ||
| 2 Diseased Vessels | ||||||
| EES | 300 | 17 | 10.14 | 1.22 [0.51, 2.95] | 0.66 | |
| CABG | 300 | 13 | 6.43 | Reference | ||
| Complete Revascularization | 0.002 | |||||
| EES | 211 | 9 | 5.77 | 0.58 [0.23, 1.48] | 0.26 | |
| CABG | 211 | 15 | 8.42 | Reference | ||
| Incomplete Revascularization | ||||||
| EES | 852 | 78 | 12.59 | 3.10 [1.87,5.13] | <0.0001 | |
| CABG | 852 | 31 | 4.81 | Reference | ||
| Outcome: Stroke | ||||||
| 3 Diseased Vessels | 0.48 | |||||
| EES | 166 | 3 | 2.58 | 0.40 [0.08, 2.06] | 0.27 | |
| CABG | 166 | 6 | 4.44 | Reference | ||
| 2 Diseased Vessels | ||||||
| EES | 300 | 9 | 6.01 | 0.83 [0.25, 2.73] | 0.76 | |
| CABG | 300 | 9 | 4.26 | Reference | ||
| Complete Revascularization | 0.50 | |||||
| EES | 211 | 5 | 3.28 | 0.38 [0.10,1.41] | 0.15 | |
| CABG | 211 | 12 | 6.68 | Reference | ||
| Incomplete Revascularization | ||||||
| EES | 852 | 23 | 4.01 | 0.62 [0.34,1.12] | 0.11 | |
| CABG | 852 | 39 | 5.71 | Reference | ||
| Outcome: Repeat Revascularization | ||||||
| 3 Diseased Vessels | 0.89 | |||||
| EES | 166 | 33 | 24.49 | 2.64 [1.32, 5.28] | 0.01 | |
| CABG | 166 | 16 | 12.45 | Reference | ||
| 2 Diseased Vessels | ||||||
| EES | 300 | 41 | 17.73 | 2.46 [1.29, 4.69] | 0.01 | |
| CABG | 300 | 24 | 11.64 | Reference | ||
| Complete Revascularization | 0.82 | |||||
| EES | 211 | 27 | 17.63 | 2.33 [1.07, 5.09] | 0.03 | |
| CABG | 211 | 15 | 10.18 | Reference | ||
| Incomplete Revascularization | ||||||
| EES | 852 | 153 | 23.35 | 2.58 [1.86,3.58] | <0.0001 | |
| CABG | 852 | 76 | 11.82 | Reference | ||
*
Event rates are based on 4 year Kaplan Meier estimates. CABG = coronary artery bypass graft surgery; EES = everolimus eluting stent; LAD= left anterior descending coronary artery.