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. 2015 Sep 2;20(9):16030–16047. doi: 10.3390/molecules200916030

Table 3.

EC50 values for the competition of the interaction NS5BΔ21: CRE with the aptamers P6-89, P6-96, P6-103, and P7-49.

Aptamer EC50 (nM) a HCV-CRE194:NS5BΔ21 Complex (%) b
P6-89 14.59 ± 1.11 5.09 ± 2.04
P6-96 38.68 ± 5.63 0.00 ± 4.15
P6-103 8.57 ± 0.58 11.98 ± 1.46
P7-49 n.d. 75.37 ± 3.05

a EC50 values were derived from the equation y = 100/(1 + 10(LogEC50−x)); b Data correspond to the highest concentration of inhibitor tested. Values are the mean of three independent assays ± the standard deviation (SD). n.d., non-determined.