. 2015 Oct 29;20(11):19660–19673. doi: 10.3390/molecules201119649

Table 1.

Epoxycarvone stereoisomers effect on pentylenetetrazole-induced seizures test.

Experimental Groups	Latency (s)	Mortality (%)
Control (Tween 80 5%)	109.9 ± 13.0	50
Diazepam (standard)	900.0 ± 0.0 ^a	0
(+)-cis-EC (7)	900.0 ± 0.0 ^a	0
(−)-cis-EC (8)	763.3 ± 69.3 ^a	0
(+)-trans-EC (9)	791.1 ± 108.9 ^a	0
(−)-trans-EC (10)	743.0 ± 83.7 ^a	0

The values represent the mean ± SEM (n = 8 in each group). ^a p < 0.001 for the epoxycarvone stereoisomers group (300 mg/kg) as compared to the control group (ANOVA One way/Tukey’s test). Fisher’s exact test was used to analyze the mortality rate.