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Surface concentrations after 10 min of dissolution of indomethacin compressed surfaces (modified from [6]).
| Sample | Concentration/mg/L | ||
|---|---|---|---|
| Distance from the Dissolution Surface | |||
| 0 mm | 2 mm | 3 mm | |
| Nanocrystals with Pluronic F 68, particle size 580 nm | 28.7 | 11.7 | 5.8 |
| Microcrystals with Pluronic F 68 | 11.4 | 4.0 | 2.6 |
| Nanocrystals with Pluronic F127, particle size 580 nm | 22.1 | 9.4 | 4.3 |
| Microcrystals with Pluronic F127 | 17.1 | 7.6 | 4.0 |
| Bulk indomethacin | 2.1 | 0.3 | 0.0 |
