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. 2015 Dec 9;20(12):22000–22027. doi: 10.3390/molecules201219816

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© 2015 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).

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Selected in vivo results with [¹¹C]erlotinib. (a) Chemical structure of [¹¹C]erlotinib and comparative PET imaging studies; (b) Bone metastasis (c) and tumor/lymph node metastasis accumulation of [¹¹C]erlotinib in non-small-cell lung carcinoma (with CT and [¹⁸F]FDG PET) (Figures in (b,c) adapted by permission from Macmillan Publishers Ltd on behalf of Cancer Research^©, UK, [70] 2011); (d) Magnetic resonance imaging-PET image from [¹¹C]erlotinib accumulation in brain metastatic lesions in a patient diagnosed with a non-small-cell lung carcinoma. (CT: computed tomography) (Adapted by permission from [71], from the publisher Wolters Kluwer).