Diminished circulating levels of IL-10 family cytokines and elevated IL-22 levels in TBL individuals. The systemic levels of IL-10, IL-19, IL-20, IL-22, IL-24, IL-26, IL-28A, IL-28B and IL-29 were measured by ELISA in TBL (n = 44), PTB (n = 44) and HC (n = 44) individuals. The data were shown as scatter plots with each circle or square or diamond indicates a single individual and the bar representing the geometric mean. P values were calculated using the Kruskal-Wallis test with Dunn multiple comparisons -*P < 0.05, **P < 0.01, ***P < 0.001 and ****P < 0.0001.