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. 2018 Oct 19;11(1):129–144. doi: 10.1080/19420862.2018.1530920

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© 2018 The Author(s). Published by Taylor & Francis.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 12. — Biological activities comparison of SB5 and the reference product with similarity range.

(A) TNF binding; Results from 13 batches of SB5, 41 lots of EU Humira®, and 40 lots of US Humira® are presented as mean ± 1SD. (B) TNF neutralization; Results from 13 batches of SB5, 40 lots of EU Humira®, and 35 lots of US Humira® are presented as box plot with min/max whiskers.