Scheme 4.
Synthesis of AT2R ligands 83–96. i) PdCl2(dppf), K2CO3, DME, H2O; j) 1. TFA; 2. butyl chloroformate, TEA, DCM (to 83–87); k) 1. TFA; 2. ethyl chloroformate, DMAP, DIPEA, DCM (to 88–96).
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.