Table 2.
Time-weighted average mean arterial pressure, systolic blood pressure, and diastolic blood pressure.
| Placebo and sumatriptana n = 34 | Erenumab and sumatriptan n = 20 | |
|---|---|---|
| Mean arterial pressure, mmHg | ||
| LS mean (SE) | 87.4 (1.0) | 87.4 (1.2) |
| Difference in LS mean (90% CI) | −0.04 (−2.2, 2.1) | |
| Systolic blood pressure, mmHg | ||
| LS mean (SE) | 120.9 (1.3) | 119.0 (1.6) |
| Difference in LS mean (90% CI) | −1.9 (−4.8, 0.9) | |
| Diastolic blood pressure, mmHg | ||
| LS mean (SE) | 70.8 (1.0) | 71.9 (1.2) |
| Difference in LS mean (90% CI) | 1.01 (−1.0, 3.0) | |
CI: confidence interval; LS: least squares; SE: standard error.
Analysis adjusted for treatment and time as covariates and subject as random effect in a linear mixed-effects model.
a
Subjects receiving sumatriptan are from group A and group B; subjects in group B received erenumab on day 5 in part 2.