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. 2019 Jan 30;14(1):e0211750. doi: 10.1371/journal.pone.0211750

Correction: Serum matrix metalloproteinase 3 levels are associated with an effect of iguratimod as add-on therapy to biological DMARDs in patients with rheumatoid arthritis

Nao Tokai, Shuzo Yoshida, Takuya Kotani, Ayaka Yoshikawa, Yuko Kimura, Youhei Fujiki, Yoko Matsumura, Tohru Takeuchi, Shigeki Makino, Shigeki Arawaka
PMCID: PMC6353179  PMID: 30699195

There is an error in the second sentence of the Subjects and Methods section. The correct sentence is: This was defined as the state of 2.6 < DAS28ESR < 5.1 or PD score ≥ 2 in at least one of the 28 joints on US examination.

There is an error in the fourth sentence of the fifth paragraph of the Discussion section. The correct sentence is: Therefore, the effects of bDMARDs on the serum MMP-3 levels could not be evaluated accurately.

There is an error in the first sentence of the eighth paragraph of the Discussion section. The correct sentence is: According to a report by Hattori et al. analyzing 114 RA patients treated with adalimumab for 52 weeks or longer, the rate of improvement of the serum MMP-3 levels after 4 weeks was significantly higher in the DAS28-CRP remission group.

In Fig 3, the headings PSL using and PSL non-using are swapped. The left side should be PSL non-using and the right should be PSL using. Please see the corrected Fig 3 here.

Fig 3.

Fig 3

Comparison of the serum MMP-3 levels at 12 weeks and the MMP-3 ratio between steroids using and non-using groups (A). Correlation between the serum MMP-3 levels at 12 weeks / the MMP-3 ratio and dosage of steroids (B). MMP-3 ratio, ratio of the serum matrix metalloproteinase 3 levels at baseline to those at 12 weeks; PSL, prednisolone.

Reference

  • 1.Tokai N, Yoshida S, Kotani T, Yoshikawa A, Kimura Y, Fujiki Y, et al. (2018) Serum matrix metalloproteinase 3 levels are associated with an effect of iguratimod as add-on therapy to biological DMARDs in patients with rheumatoid arthritis. PLoS ONE 13(8): e0202601 10.1371/journal.pone.0202601 [DOI] [PMC free article] [PubMed] [Google Scholar]

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