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. Author manuscript; available in PMC: 2020 Feb 15.
Published in final edited form as: Cancer. 2018 Nov 14;125(4):524–532. doi: 10.1002/cncr.31836

Table 3.

The association between baseline serum hormone levels and the development of any grade hypertension, hypokalemia or edema. Bolded values are statistically significant (p<0.05) using Wilcoxon’s rank sum test. All units are ng/dL. DHEA=Dehydroepiandrosterone, DHT=Dihydrotestosterone.

Hormone Toxicity N Min Q1 Median Q3 Max P-value
Androstenedione No 20 0.13 0.23 0.39 0.70 1.36 0.04
Yes 38 0.11 0.17 0.28 0.40 1.04
All 58 0.11 0.18 0.29 0.44 1.36
Androsterone No 20 0.02 0.05 0.07 0.10 0.16 0.01
Yes 38 0.01 0.02 0.04 0.07 0.13
All 58 0.01 0.03 0.05 0.09 0.16
Corticosterone No 20 0.33 0.98 1.35 2.58 7.35 0.99
Yes 38 0.38 0.98 1.35 2.24 9.62
All 58 0.33 0.98 1.35 2.58 9.62
Cortisol No 20 31.08 82.26 112.10 164.21 239.82 0.57
Yes 38 46.32 88.85 103.52 140.88 204.87
All 58 31.08 88.85 103.52 147.28 239.82
Cortisone No 20 72.09 156.91 211.48 250.49 310.90 0.25
Yes 38 81.06 146.37 181.49 214.58 317.20
All 58 72.09 151.07 187.85 237.27 317.20
DHEA No 20 0.20 0.77 1.54 2.13 6.10 0.03
Yes 38 0.17 0.44 0.73 1.49 4.50
All 58 0.17 0.60 0.90 1.72 6.10
DHT No 20 0.01 0.01 0.02 0.02 0.05 0.17
Yes 38 0.01 0.01 0.01 0.02 0.03
All 58 0.01 0.01 0.01 0.02 0.05
11-Deoxycorticosterone No 20 0.01 0.01 0.01 0.03 0.08 0.40
Yes 38 0.00 0.01 0.01 0.02 0.08
All 58 0.00 0.01 0.01 0.02 0.08
11-Deoxycortisol No 19 0.08 0.13 0.22 0.45 0.73 0.19
Yes 38 0.06 0.12 0.15 0.28 0.78
All 57 0.06 0.12 0.17 0.30 0.78
17-Hydroxypregnenolone No 20 0.19 0.19 0.63 1.31 4.78 0.08
Yes 38 0.19 0.19 0.19 0.70 3.67
All 58 0.19 0.19 0.20 1.08 4.78
17-Hydroxyprogesterone No 20 0.05 0.07 0.13 0.21 0.46 0.03
Yes 38 0.03 0.05 0.09 0.13 0.38
All 58 0.03 0.06 0.09 0.17 0.46
Pregnenolone No 19 0.13 0.20 0.33 0.49 1.13 0.06
Yes 38 0.11 0.17 0.26 0.32 0.97
All 57 0.11 0.17 0.27 0.35 1.13
Progesterone No 20 0.01 0.02 0.02 0.03 0.06 0.05
Yes 38 0.01 0.01 0.02 0.02 0.09
All 58 0.01 0.01 0.02 0.03 0.09
Testosterone No 20 0.04 0.05 0.08 0.09 0.21 0.32
Yes 38 0.02 0.04 0.07 0.10 0.34
All 58 0.02 0.05 0.07 0.09 0.34