Table 1. Frequency distribution of the DNA repair genes genotypes/alleles in patients and controls, and the risk of breast cancer.

	Patients (n = 300)		Controls (n = 300)
XRCC1-Arg399Gln	Number	(%)	Number	(%)	OR (95% CI)a	p-value
Arg/Arg	34	11.33	66	22.00	1.00 Ref
Arg/Gln	38	12.67	180	60.00	0.41 (0.23-0.70)	0.0017
Gln/Gln	228	76.00	54	18.00	8.19 (4.92-13.63)	<.0001
Arg	106	17.67	312	52.00	1.00 Ref
Gln	494	82.33	288	48.00	6.37 (4.86-8.35)	<.0001
hMSH2-Gly322Asp	Number	(%)	Number	(%)	OR (95% CI)	p-value
Gly/Gly	42	14.00	80	26.67	1.00 Ref
Gly/Asp	51	17.00	177	59.00	0.54 (0.33-0.89)	0.021
Asp/Asp	207	69.00	43	14.33	9.16 (5.57-15.07)	<.0001
Gly	135	22.5	337	56.17	1.00 Ref
Asp	465	77.5	263	43.83	4.41 (3.43-5.67)	<.0001
XPD-Lys751Gln	Number	(%)	Number	(%)	OR (95% CI)	p-value
Lys/Lys	54	18.00	96	32.00	1.00 Ref
Lys/Gln	70	23.33	120	40.00	1.03 (0.66-1.37)	1.000
Gln/Gln	176	58.67	84	28.00	3.72 (2.44-5.68)	<.0001
Lys	178	29.67	312	52.00	1.00 Ref
Gln	422	70.33	288	48.00	2.56 (2.02-3.25)	<.0001
XRCC2-Arg188His	Number	(%)	Number	(%)	OR (95% CI)	p-value
Arg/Arg	72	24.00	80	26.67	1.00 Ref
Arg/His	110	36.67	106	35.33	1.15 (0.76-1.74)	0.571
His/His	118	39.33	114	38.00	1.15 (0.76-1.73)	0.571
Arg	254	42.33	266	44.33	1.00 Ref
His	346	57.67	334	55.67	1.08 (0.86-1.36)	0.521
RAD51-4719A/T	Number	(%)	Number	(%)	OR (95% CI)	p-value
A/A	60	20.00	75	25.00	1.00 Ref
A/T	126	42.00	150	50.00	1.05 (0.69-1.58)	0.887
T/T	114	38.00	75	25.00	1.90 (1.21-2.97)	0.007
A	246	41.00	300	50.00	1.00 Ref
T	354	59.00	300	50.00	1.44 (1.15-1.80)	0.002
RAD51-4601A/G	Number	(%)	Number	(%)	OR (95% CI)	p-value
A/A	78	26.00	87	29.00	1.00 Ref
A/G	138	46.00	123	41.00	1.25 (0.84-1.84)	0.305
G/G	84	28.00	90	30.00	1.04 (0.67-1.59)	0.920
A	294	49.00	297	49.50	1.00 Ref
G	306	51.00	303	50.50	1.02 (0.81-1.27)	0.920

^aCrude odds ratio (OR), 95% CI = confidence interval at 95%.