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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Platelets. 2017 Nov 28;30(1):88–97. doi: 10.1080/09537104.2017.1378807

Figure 5. Effect of ITP on endothelial ultrastructure.

Figure 5.

A) Vessel thickness, (B) number of endothelial pinocytotic vesicle score, (C) large vacuole score, and (D) number of spaces between cells. **There is a significant decrease in number pinocytotic vesicles from baseline to 24 hours of thrombocytopenia compared to time-matched controls (P<0.0357). See text for vacuole and vesicle scoring system. Symbols represent the mean value for all capillaries evaluated in each dog at that time point. Bars represent overall treatment group mean. n=5 2F9 treated dogs; n = 3 control dogs.