Table 1.

Ultrastructural features of endothelium in healthy dogs and dogs after 24 hours of severe thrombocytopenia.

	Treated (n=5)			Control (n=3)
	Baseline	24 hours	Difference	Baseline	24 hours	Difference
Vessel thickness (μm)	0.78±0.42	0.71±0.38	-0.08±0.57	0.76±0.39	0.75±0.38	-0.01±0.55
Pinocytotic vesicle score	2.41±0.48	2.16±0.53	-0.25±0.71**	2.28±0.57	2.59±0.51	0.31±0.76
Large vacuole score	0.71±0.77	0.83±0.86	0.13±1.16	0.84±0.78	0.91±0.79	0.07±1.11
Number of spaces between cells	0.69±0.7	0.84±0.79	0.15±1.06	0.73±0.6	0.81±0.69	0.08±0.92

See methods for vesicle and vacuole scoring system. Results are mean ± S.D.

^**P<0.0357 compared to change in time-matched controls.