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. 2018 Dec 29;11(1):19. doi: 10.3390/v11010019

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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ZIKV plasmablast responses enhance DENV2 infection in vitro. (A) Representative flow cytometry plots comparing ADE activity of plasma from ZK016 vs. healthy control. Boxed population represents DENV2-infected cells based on positive 4G2 staining. Plots shown display ADE at plasma dilution of 1:3000. (B) DENV2 ADE activities of plasma from ZK016, ZK018 and a flavivirus-naïve healthy donor (dotted line). (C) DENV2 ADE activities of FL-specific and non FL-specific mAbs from ZK016 and ZK018.