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. 2019 Jan 31;5(1):e01161. doi: 10.1016/j.heliyon.2019.e01161

Table 2.

Anthelmintic Medicinal plants; it active principles and anti-nutrients.

Plant Anthelmintic active principle (s) Part used Tested organism Anti-nutrient Reference (s)
Carica papaya L. papain (papaya proteinase I) and Benzyl isothiocyanate Leaves, fruit and seed Trichostrongylus colubriformis, Ascaris suum phytate, oxalate, condensed tannin and hydrolysable tannin Hounzangbe-Adote et al. (2005); Adetuyi et al. (2008); Bauri et al. (2015)
Butea monosperma Lam. Palasonin and Tannins Seed, root, flower and leaves Ascaris lumbricoides, Dipylidium caninum, Toxocara canis Protease inhibitors Mishra et al., 2000; Pandey and Jamal (2010); Bauri et al. (2015)
Terminalia arjuna Wight and Arn. Tannin and ellagic acid leaf, bud, seed, root and stem Eggs, larvae and adult of Haemonchus contortus Phytic acid, tannin Bauri et al. (2015)
Allium sativum L. Allicin bulbs, Ascaridia galli, Haemonchus contortus Hydrocyanic acid, oxalate, phytic acid, cyanogenic glycoside Kavindra Singh and Nagaich, 2000; Iqbal et al. (2001); Asanga et al. (2015)
Cucurbita maxima Duchesne Cucurbitin Seeds Ascaris lumbricoides, Hymenolepis diminuta Akaloids, saponins, Tannin, Cyanide, Oxalate, phytate Iqbal et al. (2001); Mohaammed et al. (2014)
Zingiber officinale Roscoe Zingiberene, bisabolene, gingerols and shogaols Rhizome Haemonchus contortus Tannin, Phytin and Oxalate Iqbal et al. (2001); Adanlawo and Dairo (2007)
Nigella sativa L. Thimoquinone and Dithimoquinone Seeds Schistosoma mansoni Trypsin inhibitor, phytic acid Kailani et al. (1995); Bauri et al., 2015
Piper longum L. piperine Fruit and leaves Ascaris lumbricoides Tannin Bauri et al. (2015); Singh et al. (2015)
Ocimum sanctum L. Eugenol, ß-caryophyllene and Urosilic acid Leaf Caenorhabditis elegans, Ascaridia galli Phytin, Oxalate, Tannic acid, Phytic acid Asha et al. (2001)
Azadirachta indica A. Juss. Azadirachtin Leaves Fasciola gigantica condensed tannins, crude saponins, oxalate, lignin, azadirachtin Kushwaha et al. (2004); Adjorlolo et al. (2016)
Moringa oleifera Lam. Tannins, Flavonoids, Triterpeniods, Saponins and Alkaloids Leaf and seed Dracunculus medinensis, Schistosoma mansoni Oxalates, Alkaloids, Phytate, Tannin Stevens et al. (2015)
Artemisia annua L. Artemisinin, Quercetin Leaf Fasiola hepatica, Schistosoma mansoni Phytate, Tannin Brisibe et al. (2009); Dragan et al. (2014)
Cymbogon martini (Roxb.) Wats. Geranio Whole Plant Caenorhabditis elegans McGaw et al. (2001)
Mentha cordifolia Lej. & Courtois auct. Glucosides, b-Sitosterols, Leaf Ascaris suum Villaseñor et al. (2002)
Calotropis procera (Aiton) W.T. Aiton Anthocyanins, Triterpenoids, alkaloids Leaf Haemonchus contortus Phytic acid, Tannins, Oxalate Adebayo et al., 2015, Al-Qarawi et al., 2001
Aloe ferox Mill. Phenol
Saponin
Alkaloids
Flavonoids
Leaf Trichuris spp. Tannin, Oxalate, Phytate Adesuyi and Awosanya (2012); Maphosa and Masika (2012)