Table 5.
Parameter | Source | Sum of Squares | df | Mean Square | F | Sig. |
---|---|---|---|---|---|---|
Cmax (ng/mL) | Between Groups | 3,131,899.76 | 2 | 1,565,949.88 | 4584.19 | <0.001 |
Within Groups | 5123.96 | 15 | 341.597 | |||
Total | 3,137,023.72 | 17 | ||||
Tmax (hr) | Between Groups | 0.444 | 2 | 0.222 | 16.84 | |
Within Groups | 0.198 | 15 | 0.013 | |||
Total | 0.642 | 17 | ||||
AUC (0–24) (ng·hr/mL) | Between Groups | 106,305,369.09 | 2 | 53,152,684.55 | 285.95 | |
Within Groups | 2,788,214.49 | 15 | 185,880.97 | |||
Total | 109,093,583.59 | 17 | ||||
AUC (0–α) (ng·hr/mL) | Between Groups | 108,822,905.28 | 2 | 54,411,452.64 | 255.43 | |
Within Groups | 3,195,313.44 | 15 | 213,020.89 | |||
Total | 112,018,218.72 | 17 | ||||
K (hr−1) | Between Groups | 0.001 | 2 | 0.001 | 9.38 | 0.002 |
Within Groups | 0.001 | 15 | 0.000 | |||
Total | 0.003 | 17 | ||||
t1/2 (hr) | Between Groups | 0.804 | 2 | 0.402 | 8.88 | 0.003 |
Within Groups | 0.679 | 15 | 0.045 | |||
Total | 1.482 | 17 |
df: degree of freedom.