Table 2.
Antimicrobial activity of natural CDXs with pyran groups.
| No. | Name/Structure | Antimicrobial Activity (MIC) |
|---|---|---|
| 6N | Mangostanol
|
M. tuberculosis H37Ra (200 µg/mL) |
| 7N | Tovophyllin-B
|
M. tuberculosis H37Ra (25 µM) |
| 8N | Calozeyloxanthone
|
17 MRSA strains and 25 MSSA strains (range 4.1–8.1 µg/mL) |
| 9N | Smeathxanthone B
|
Escherichia coli (625 µg/mL), Klebsiella pneumoniae (625 µg/mL), Proteus vulgaris (312.5 µg/mL), S. typhi (625 µg/mL), S. faecalis (625 µg/mL), C. albicans (312.5 µg/mL), C. krusei (312.25 µg/mL) |
| 10N | Artoindonesianin-C
|
M. tuberculosis H37Ra (12.5 µM) |
| 11N | Cowagarcinone-D
|
MRSA-SK1 (128 µg/mL); S. aureus (inactive); E. coli (128 µg/mL); Salmonella typhimurium (128 µg/mL) |
MIC: Minimum inhibitory concentration; MRSA: Methicillin-resistant S. aureus; MSSA: Methicillin-sensitive S. aureus; * Stereogenic center.