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. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: Resuscitation. 2018 Oct 3;133:101–107. doi: 10.1016/j.resuscitation.2018.09.011

Table 3.

Cause of Death by Study Day.

Hypothermia
Study Day

0 1 2 3 4 5 > 5 Overall
(N = 5) (N = 30) (N = 17) (N = 14) (N = 21) (N = 9) (N = 83) (N = 179)

Cause of Death
 Cardiovascular failure/futility 4 (80.0%) 8 (26.7%) 7 (41.2%) 2 (14.3%) 1 (4.8%) 0 (0.0%) 16 (19.3%) 38 (21.2%)
 Brain death declared 0 (0.0%) 3 (10.0%) 2 (11.8%) 4 (28.6%) 12 (57.1%) 6 (66.7%) 17 (20.5%) 44 (24.6%)
 Withdrawal for poor neurologic prognosis 0 (0.0%) 11 (36.7%) 5 (29.4%) 6 (42.9%) 8 (38.1%) 3 (33.3%) 31 (37.3%) 64 (35.8%)
 Respiratory failure/futility 0 (0.0%) 1 (3.3%) 1 (5.9%) 0 (0.0%) 0 (0.0%) 0 (0.0%) 3 (3.6%) 5 (2.8%)
 Withdrawal for other system failure 1 (20.0%) 3 (10.0%) 2 (11.8%) 2 (14.3%) 0 (0.0%) 0 (0.0%) 6 (7.2%) 14 (7.8%)
 Other/Unknown 0 (0.0%) 4 (13.3%) 0 (0.0%) 0 (0.0%) 0 (0.0%) 0 (0.0%) 10 (12.0%) 14 (7.8%)
Normothermia
Study Day

0 1 2 3 4 5 > 5 Overall
(N = 19) (N = 29) (N = 22) (N = 22) (N = 18) (N = 10) (N = 65) (N = 185)
Cause of Death

 Cardiovascular failure/futility 12 (63.2%) 6 (20.7%) 2 (9.1%) 3 (13.6%) 1 (5.6%) 2 (20.0%) 20 (30.8%) 46 (24.9%)
 Brain death declared 0 (0.0%) 11 (37.9%) 11 (50.0%) 8 (36.4%) 7 (38.9%) 5 (50.0%) 4 (6.2%) 46 (24.9%)
 Withdrawal for poor neurologic prognosis 3 (15.8%) 9 (31.0%) 6 (27.3%) 9 (40.9%) 9 (50.0%) 2 (20.0%) 20 (30.8%) 58 (31.4%)
 Respiratory failure/futility 0 (0.0%) 1 (3.4%) 0 (0.0%) 1 (4.5%) 0 (0.0%) 0 (0.0%) 8 (12.3%) 10 (5.4%)
 Withdrawal for other system failure 2 (10.5%) 2 (6.9%) 2 (9.1%) 0 (0.0%) 0 (0.0%) 0 (0.0%) 6 (9.2%) 12 (6.5%)
 Other/Unknown 2 (10.5%) 0 (0.0%) 1 (4.5%) 1 (4.5%) 1 (5.6%) 1 (10.0%) 7 (10.8%) 13 (7.0%)