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. 2019 Jan 22;8:e41542. doi: 10.7554/eLife.41542

Figure 6. RMTg lesions disrupt conditioned place aversion to a wide range of stimuli.

(A) Photographs of immunostaining of NeuN in RMTg region with and without excitotoxic lesions. Scalebar: 100 µm. RMTg-lesions reduced place aversion scores as measured by relative time spent in stimulus-paired versus unpaired chambers (B), and abolished place aversion as measured by relative entries into paired versus unpaired chambers (C). (D) RMTg lesions did not alter total entries into chambers. (E) RMTg-lesioned rats lacked the training-induced reduction in locomotion seen in shams (F, G).

Figure 6.

Figure 6—figure supplement 1. Excitotoxic lesion placements in the RMTg.

Figure 6—figure supplement 1.

RMTg (black circles) lesion sizes (yellow) in conditioned place aversion experiments.