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Journal of Cardiothoracic Surgery logoLink to Journal of Cardiothoracic Surgery
. 2019 Feb 5;14:31. doi: 10.1186/s13019-019-0850-x

Correction to: Predictive risk factors for lymph node metastasis in patients with resected non-small cell lung cancer: a case control study

Yusef Moulla 1,, Tanja Gradistanac 2, Christian Wittekind 2, Uwe Eichfeld 1, Ines Gockel 1, Arne Dietrich 1
PMCID: PMC6364423  PMID: 30722784

Correction to: J Cardiothorac Surg

https://doi.org/10.1186/s13019-019-0831-0

The original article [1] contains slight errors whereby several terms in the first column of Tables 1, 2, and 3 have an erroneous ‘p’ preceding them. The correct presentation of these tables can be viewed ahead.

Table 1.

Main characteristics of the patients, pTNM-Classification 2017, 8th Edition

Characteristics Number of Patients (n) Percentage
Tumor-localization
 central 53 26.2%
 peripheral 149 73.8%
Histology
 adenocarcinoma 117 57.4%
 SCCa 75 36.8%
 others 12 5.9%
Grading
In situ 2 1%
 G1 25 12.4%
 G2 95 47.0%
 G3 68 33.3%
 G4 12 5.9%
pT-category
pTis 2 1%
pT1 90 45.1%
 pT1a 10 4.9%
 pT1b 37 18.1%
 pT1c 43 21.1%
pT2 44 26.5
 pT2a 39 19.1%
 pT2b 15 7.4%
pT3 35 17.2%
pT4 23 11.3
pN-category
 pN0 126 61.8%
 pN1 33 16.2%
 pN2 45 22%
pM-category
 pM0 193 94.5%
 pM1a 5 2.5%
 pM1b 5 2.5%
 pM1c 1 0.5%
 L-Status
 L0 57 28.1%
 L1 146 71.9%
 V-Status
 V0 165 81.3%
 V1 38 18.7%

aSCC Squamous cell carcinoma

Table 2.

Univariate Analysis of positive pulmonary and mediastinal lymph nodes (pN1+, pN2+)

Variables pN1- (%) pN1+ (%) P-Value pN2- (%) pN2+ (%) P-Value
Sex 0.148 0.627
 male 90 (63.4) 52 (36.6) 112 (78.9) 30 (21.1)
 female 46 (74.2) 16 (25.8) 47 (75.8) 15 (24.2)
Age 0.298 0.237
 ≤ 68 years 68 (63) 40 (37) 88 (81.5) 20 (81.5)
 > 68 years 68 (70.8) 28 (29.2) 71 (74.0) 25 (21.2)
Tumor site 0.067 0.783
 right 90 (71.4) 36 (28.6) 99 (78.6) 27 (21.4)
 left 46 (59) 32 (41) 60 (76.9) 18 (23.1)
Tumor localization < 0.001 0.02
 central 25 (47.2) 28 (52.8) 36 (66.7) 18 (33.3)
 peripheral 111 (74.5) 38 (25.5) 122 (81.9) 27 (18.1)
Tumor size 0.011 0.042
 ≤ 3 cm 77 (75.5) 25 (24.5) 86 (84.3) 16 (15.7)
 > 3 cm 59 (57.8) 43 (42.8) 73 (71.6) 29 (28.4)
Lobe distribution 0.918 0.385
 ULa 85 (66.4) 43 (33.6) 97 (75.8) 31 (24.2)
 Non-UL 51 (67.1) 25 (32.9) 62 (81.6) 14 (18.4)
pT-category 0.015 0.081
 pT1 70 (77.8) 20 (22.2) 77 (85.6) 13 (14.4)
 pT2 33 (61.1) 21 (38.9) 40 (74.1) 14 (25.9)
 pT3 18 (51.4) 17 (48.6) 23 (65.7) 12 (34.3)
 pT4 13 (56.5) 10 (43.5) 17 (73.9) 6 (26.1)
R-classification 0.017 0.088
 R0 130 (68.8) 59 (31.2) 150 (79.4) 39 (20.6)
 R1–2 5 (35.7) 9 (64.3) 8 (57.1) 6 (42.9)
L-status < 0.001 < 0.001
 L0 55 (96.5) 2 (3.5) 56 (98.2) 1 (1.8)
 L1 80 (54.8) 66 (45.2) 102 (69.9) 44 (30.1)
V-status 0.006 0.004
 V0 117 (70.9) 48 (29.1) 135 (81.1) 30 (18.2)
 V 18 (47.4) 20 (52.6) 23 (60.5) 15 (39.5)
Pn-Status 0.088 0.34
 Pn0 131 (67.9) 62 (32.1) 149 (77.2) 44 (22.8)
 Pn1 4 (40.0) 6 (60.0) 9 (90.0) 1 (10.0)
Histological tumor type 0.214 0.646
 Adeno-Ca.b 84 (71.8) 33 (28.2) 94 (80.3) 23 (19.7)
56 (74.4) 19 (25.6)
 SCCc 45 (60.0) 30 (40.0) 9 (75.0) 3 (25.0)
 others 7 (58.3) 5 (41.7)
Grading 0.016 0.001
 G1 25 (89.3) 3 (10.7) 27 (96.4) 1 (3.6)
 G2 64 (67.4) 31 (32.6) 79 (83.2) 16 (16.8)
 G3 39 (57.4) 29 (42.6) 43 (63.2) 25 (36.8)
 G4 7 (58.3) 5 (41.7) 9 (75.0) 3 (25.0)

aUL Upper lobe, bAdeno-Ca. Adenocarcinoma, cSCC Squamous cell carcinoma

Table 3.

Univariate Analysis of positive lymph nodes (pN0, pN+)

Variables pN0 (%) pN+ (%) P-Value
Sex 0.397
 male 85 (59.9) 57 (40.1)
 female 41 (66.1) 21 (33.9)
Age 0.314
 ≤ 68 years 63 (58.3) 45 (41.7)
 > 68 years 63 (65.6) 33 (34.4)
Tumor site 0.067
 Right 84 (66.7) 42 (33.3)
 Left 42 (53.8) 36 (46.2)
Tumor localization < 0.001
 central 22 (41.5) 31 (58.5)
 peripheral 104 (69.8) 45 (30.2)
Tumor size < 0.001
 ≤ 3 cm 76 (74.5) 26 (25.5)
 > 3 cm 50 (49) 52 (51)
Lobe distribution 0.834
 UL a 78 (60.9) 50 (39.1)
 Non-UL 40 (62.5) 24 (37.5)
Number of dissected LN b 0.005
pT-category 0.001
 pT1 69 (76.7) 21 (23.3)
 pT2 27 (50.9) 26 (49.1)
 pT3 17 (47.2) 19 (52.8)
 pT4 11 (47.8) 12 (52.2)
R-classification 0.048
 R0 120 (96.0) 5 (4.0)
 R1–2 69 (88.5) 9 (11.5)
L-status < 0.001
 L0 54 (94.7) 3 (5.3)
 L1 71 (48.6) 75 (51.4)
V-status 0.001
 V0 111 (67.3) 54 (32.7)
 V1 14 (36.8) 24 (63.2)
Pn-status 0.188
 Pn0 121 (96.8) 4 (3.2)
 Pn1 72 (92.3) 6 (7.7)
Histological tumor type 0.141
 Adeno-Ca.b 79 (67.5) 38 (32.5)
 SCCc 41 (54.7) 34 (45.3)
 others 6 (50.0) 6 (50.0)
Grading 0.005
 G1 22 (88.0) 3 (12.0)
 G2 60 (63.2) 35 (36.8)
 G3 34 (50.0) 34 (50.0)
 G4 6 (50.0) 6 (50.0)

aUL Upper lobe, bAdeno-Ca. Adenocarcinoma, cSCC Squamous cell carcinoma

Reference

  • 1.Moulla Y, et al. Predictive risk factors for lymph node metastasis in patients with resected non-small cell lung cancer: a case control study. J Cardiothorac Surg. 2019;14:11. doi: 10.1186/s13019-019-0831-0. [DOI] [PMC free article] [PubMed] [Google Scholar]

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