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. 2019 Feb 6;6(3):1970014. doi: 10.1002/advs.201970014

High‐Throughput Screening: One‐Step Generation of a Drug‐Releasing Hydrogel Microarray‐On‐A‐Chip for Large‐Scale Sequential Drug Combination Screening (Adv. Sci. 3/2019)

Seo Woo Song 1, Su Deok Kim 1, Dong Yoon Oh 2, Yongju Lee 1, Amos Chungwon Lee 4, Yunjin Jeong 1, Hyung Jong Bae 5, Daewon Lee 3, Sumin Lee 1, Jiyun Kim 6, Sunghoon Kwon 1
PMCID: PMC6364504

Abstract

The need for a robotic pipetting machine to manage several substances limits the accessibility of high‐throughput screening techniques for general researchers. In article number 1801380, Jiyun Kim, Sunghoon Kwon, and co‐workers report a method to generate a large‐scale heterogeneous drug‐releasing‐microarray via a “pipetting‐free” manner by self‐assembly of encoded drug‐laden microparticles on the array of microwells.

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Keywords: drug‐laden hydrogel, encoded microparticle, high‐throughput screening, self‐assembly, sequential combination


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