Complete Disruption of Autism-Susceptibility Genes by Gene Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons

(Stem Cell Reports 11, 1211–1225; January 13, 2018)

The original representative trace of excitatory post-synaptic current (EPSC) for AFF2^−/y was used twice by mistake to generate the ASTN2^−/y cropped trace on the top panel of Figure 5A. However, we confirm that the original data was not a duplicate; only the image file was cropped incorrectly as a display figure for the trace. We have made a new Figure 5 with the correct ASTN2 trace cropped in Figure 5A. None of the original data or interpretation of the data was impacted.

Figure 5.

Electrophysiological Phenotyping of KO iPSC-Derived Neurons (corrected)

Figure 5.

Electrophysiological Phenotyping of KO iPSC-Derived Neurons (original)