Comparison of Malondialdehyde (MDA) between pre and post administration of Crocin in all groups in the whole brain tissue after 21 days with oral administration (100 mg/kg) in demyelinated Wistar rats. Data are presented as Mean ± SEM and analyzed by Paired t test. MDA; Malondialdehyde, U/mg; Unit per milligram, SO; Sham operated, ST; Sham treatment, Treat; Treatment, SEM; Standard error mean,***; p < 0.001 compared to pre-test.