Figure 4. Tumor protection in prophylactically vaccinated mice.

Vaccinated BALB/c mice (dark lines) were challenged s.c. with 5 × 10⁵ CT26 cells and tumor growth was assessed every 2–3 days. PBS injected mice served as negative controls (light grey lines) (n = 8). Each line represents a single mouse in the course of the experiment. (A) Mice were vaccinated with Ad5-MelARV only (n = 7), (B) with DNA-MelARV and Ad5-MelARV in a prime-boost regimen (n = 8), or (C) with DNA-MelARV only (n = 7).