Skip to main content
Clinical Case Reports logoLink to Clinical Case Reports
. 2019 Jan 31;7(3):580–582. doi: 10.1002/ccr3.2006

Fatal middle cerebral artery aneurysm from Mycobacterium tuberculosis infection

Shan Lin 1, Yan Wang 1, Wei Guan 1,
PMCID: PMC6406166  PMID: 30899501

Key Clinical Message

Aneurysms caused by Mycobacterium tuberculosis infection are a rare disease. For such patients, cerebral artery aneurysm is a rare but evenly fatal lesion that is not diagnosed in time; combined antituberculosis treatment and surgical intervention provide the best chance of cure.

Keywords: antituberculosis, artery aneurysm, Mycobacterium tuberculosis infection, surgical intervention


A 37‐year‐old woman presented to intensive care unit (ICU) with a headache, nausea and convulsions for 8 hours. One month ago, the diagnosis was confirmed as pulmonary tuberculosis, and there was no abnormality in the head CT at that time. Regular antituberculosis treatment was given. But the patient gradually developed headache, nausea, and worsened. Analysis of the cerebrospinal fluid (CSF) showed lymphocyte‐dominant pleocytosis, decreased of glucose and chloride, a pressure of more than 330 mm H2O. Emergency chest CT (Figure 1) and cranial CT (Figures 2 and 3) were performed. For the sake of patient safety, we gave an emergency interventional treatment and continued to give regular antituberculosis treatment. After 2 weeks of treatment, the symptoms of headache and nausea disappeared. So far, she is still in follow‐up.

Figure 1.

Figure 1

Chest CT showed solidation, infiltration, cavity, calcification and satellite foci in the upper lungs

Figure 2.

Figure 2

Head CT showed left middle cerebral artery aneurysm

Figure 3.

Figure 3

The three dimensional (3D) reconstruction with CT angiography showed artery aneurysm with a size of 4.4*4.6 mm

Aneurysms caused by Mycobacterium tuberculosis infection are a rare disease. It has been reported that the ascending aorta, abdominal aorta, and thoracic aorta can be involved,1, 2 but the middle cerebral artery aneurysms caused by tuberculosis has not been reported. For such patients, cerebral artery aneurysm is a rare but evenly fatal lesion that is not diagnosed in time; combined antituberculosis treatment and surgical intervention provide the best chance of cure.

CONFLICT OF INTEREST

None declared.

AUTHOR CONTRIBUTION

Shan lin and Yan Wang wrote the draft of this article. Wei Guan revised this article. Shan Lin and Yan Wang contributed equally to this work. Written consent to publication was obtained.

Lin S, Wang Y, Guan W. Fatal middle cerebral artery aneurysm from Mycobacterium tuberculosis infection. Clin Case Rep. 2019;7:580–582. 10.1002/ccr3.2006

REFERENCES

  • 1. Long R, Guzman R, Greenberg H, et al. Tuberculous mycotic aneurysm of the aorta: review of published medical and surgical experience. Chest. 1999;115(2):522‐531. [DOI] [PubMed] [Google Scholar]
  • 2. Felson B, Akers PV, Hall GS, et al. Mycotic tuberculous aneurysm of the thoracic aorta. JAMA. 1977;237(11):1104‐1108. [PubMed] [Google Scholar]

Articles from Clinical Case Reports are provided here courtesy of Wiley

RESOURCES