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. 2019 Feb 22;8(2):195. doi: 10.3390/cells8020195

Table 2.

Preclinical studies of tankyrase inhibitors with in vivo murine fibrosis models.

Disease Models Drugs References
Bleomycin-induced dermal fibrosis model XAV939 [42]
TGF-β receptor I-overexpressing model XAV939 [42]
Bleomycin pulmonary fibrosis model XAV939 [45]