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The influence of histamine on the secretion of von Willebrand factor (vWF) in the absence or presence of VAS2870. HUVECs were incubated at 30 °C during 5 min with 10 μM VAS2870 or vehicle (DMSO at final concentration 0.1% in the wells of a 48-well plate. Then, 100 μM histamine, or PSS as a vehicle control, were added to the cells, and they were additionally incubated for 30 min. Each value is a mean of the data from three independent experiments.
