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. 2019 Feb 21;11(2):183. doi: 10.3390/v11020183

Figure 1.

Figure 1

Sin Nombre virus (SNV) replication and shedding in male and female deer mice of different ages. (A) Groups of 1–2-month-old deer mice were inoculated with a VeroE6-adapted SNV. n = 4. (B) and (C) Groups of 10 (intramuscularly (IM) infected) or 12 (intraperitoneally (IP) infected) deer mice were infected with SNV, and S segment copies were detected in (B) pooled lung homogenates from each group for producing viral stocks or (C) each individual mouse to determine the amounts of viral replication and shedding. (B) 1 IM group was tested, and 3 IP groups were tested. (D) and (E) Comparison of replication and shedding seen in (D) male vs. female deer mice 10 days post-infection (circles: 1–2-month-old deer mice; triangles: 5–6-month-old deer mice) or (E) 1–2-month-old (young) vs. 5–6-month-old (old) deer mice 10 days post-infection (circles: male deer mice; triangles: female deer mice). The data shown are the mean + SEM (B) and medians (C–E) for each group. The numbers indicate the p value as assessed by a Mann–Whitney test.