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. 2019 Mar 8;7:e6589. doi: 10.7717/peerj.6589

Figure 4. Transplantation of osteo-inductive PDLCs and hMSCs with HA/TCP scaffolds to SCID mice.

Figure 4

After 12 weeks, the transplants were taken out and performed HE staining. (A) Cell-free HA/TCP control. No evident bone formed or fiber cluster appeared. (B) In hMSCs-loaded HA/TCP samples, ectopic bone formation was found, but no obvious fiber bundles appeared. (C–D) In the PDLCs-loaded HA/TCP samples, massive fiber bundles linked or circled the scaffold (C, arrow) were found while the bone-like structure was limited (D, arrows). Scale bars, 100 μm.