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. 2019 Feb 25;11(2):483. doi: 10.3390/nu11020483

Figure 2.

Figure 2

Effects of ergosterol on body weight, fasting blood glucose, serum insulin, C-peptide, and renal functional parameters in streptozotocin (STZ)-induced diabetic mice. (A) Body weight, (B) fasting blood glucose, (C) serum insulin, (D) C-peptide, (E) kidney index, (F) 24-h urine volume, (G) Alb, (H) SCR, (I) BUN, and (J) TC. Alb: 24-h urinary albuminuria; SCR: serum creatinine; BUN: blood urea nitrogen; TC: total cholesterol; NC: normal control; DN: diabetic nephropathy model induced by STZ; ENA: positive control, 1.5 mg/kg/day enalaprilat administration; ERG10, ERG20, ERG40: 10, 20, 40 mg/kg/day ergosterol administration, respectively. Data are presented as the means ± SD, n = 6. *** p < 0.001 compared with the NC group; # p < 0.05, ## p < 0.01, ### p < 0.001 compared with the DN group.