TABLE 1.

Molecular characteristics of IBV NA-specific hMAbs^a

Subject	hMAb	Native isotype	Heavy chain			Light chain
			Gene usage	Mutation (% NT/% AA)	HCDR3 AA seq	Gene usage	Mutation (% NT/% AA)	LCDR3 AA seq
134	1086C12	IgG1	VH3-30 DH3-22 JH5	9/15	ARDAGCDSVGYYPGRL	Vλ1-47 Jλ2	4/6	AAWDDSLSGHLV
134	1086F8	IgG1	VH3-30 DH3-22 JH4	7/10	ARDAGYDSRGYLPGPY	Vλ1-47 Jλ2	7/10	AAWDDSLSGHVM
105	1092D4	IgG1	VH3-23 DH3-3 JH4	8/9	AKDNQDLDLWSGSYKGTFDD	Vλ6-57 Jλ3	4/7	QSYDSSRYWV
105	1092C7	IgG1	VH3-23 DH3-3 JH4	8/8	AKDKQDLDLWSGSYKGTFDE	Vλ6-57 Jλ3	4/6	QSYDSSRYWV
105	1092E10	IgG1	VH3-15 DH3-16 JH6	6/9	SAAPFTESNGYKSWDYLYGMDV	Vλ3-1 Jλ1	5/11	QAWDSNSYV
105	1092C6	IgA1	VH4-59 DH1-26 JH5	5/10	ARYRVSGNYYDTPWFDP	Vλ3-25 Jλ2	5/9	QSAASSYGYVV

^aAA, amino acids; NT, nucleotides.