Skip to main content
. 2019 Jan 31;79(Suppl 1):11–16. doi: 10.1007/s40265-018-1019-y

Table 1.

Studies prospectively evaluating HRQOL without intervention/medication

Study, year Instrument used Poor QOL compared with patients without HE
Groeneweg et al., 1998 [36] Sickness Impact Profile Yes
Schomerus and Hamster, 2001 [37] Sickness Impact Profile Yes
Arguedas et al., 2003 [4] SF-36 Yes
Bao et al., 2007 [38] Chronic Liver Disease Q, SF-36 Yes
Zhou et al., 2009 [39] Chinese adaptation of QOL Yes
Les et al., 2010 [40] Chronic Liver Disease Q, SF-36 Yes
Bajaj et al., 2011 [41] PROMIS tools and Sickness
Impact Profile
Yes
Moscucci et al., 2011 [42] SF-36 No
Parkash et al., 2012 [43] Chronic Liver Disease Q Yes
Les et al., 2010 [40] SF-36 No
Wunsch et al., 2013 [44] Chronic Liver Disease Q, SF-36 No
Ahluwalia et al., 2013 [45] Sickness Impact Profile Yes
Wang et al., 2013 [46] Chinese HRQoL instrument Yes
Nardelli et al., 2013 [47] SF-36 Yes
Thiele et al., 2013 [48] Chronic Liver Disease Q No
Mina et al., 2014 [49] Chronic Liver Disease Q Yes
Barboza et al., 2016 [50] Specific and general questionnaires Yes
Paulson et al 2016 [51] SF-36 Yes
Bajaj et al., 2016 [52] PROMIS tools Yes
Patidar et al., 2017 [10] PROMIS tools Yes
Labenz et al., 2018 [53] Chronic Liver Disease Q Yes

SF-36 Short-Form 36, PROMIS Patient-Reported Outcomes Measurement Information System, Chronic Liver Disease Q Chronic liver disease questionnaire, HRQOL health-related quality of life, QOL quality of life, HE hepatic encephalopathy