Table 4.

Inhibition of ADP-induced platelet aggregation in presence of dimeric disintegrins

Disintegrin	Type	Origin	Activity	References
CC5	Homodimer	North African Cerastes cerastes	93 nM*	Calvete et al. (2002)
CC8A/CC8B	Heterodimer	North African Cerastes cerastes	11 nM*	Calvete et al. (2002)
Contortrostatin	Homodimer	A. contortrix contortrix	60 nM*	Zhou et al. (2000)
Bilitoxin 1	Homodimer	Agkistrodon billineatus	NA*	Nikai et al. (2000)
Piscivostatin	Heterodimer	A. piscivorus piscivorus	103 nM*	Okuda and Morita (2001)
Acostatin	Heterodimer	A. c. contortrix	103 nM*	Okuda and Morita (2001)
EC3ATEC3B	Heterodimer	Echis carinatus	1000 nM*	Marcinkiewicz et al. (1999a)
EMF10A/EMF10 B	Heterodimer	Eristocophis macmahoni	1600 nM*	Marcinkiewicz et al. (1999b)
EC6ATEC6B	Heterodimer	Echis carinatus	> 1000 nM*	Marcinkiewicz et al. (2000)
Lebein	Heterodimer	Vipera lebetina	160 nM*	Gasmi et al. (2001)
Pictistatin1	¶	A. c. pictigaster	980 nM‡	This study
Pictistatin 2	Heterodimer	A. c. pictigaster	NA‡	This study

^*The activity was measured using platelet rich plasma (PRP)

^‡The activity was measured using whole blood

NA: No activity

^¶Dimer disintegrin has not been identified as either a homo or hetero