Table 1.

GRP94 KO and GRP94 ATPase inhibition lead to diminished content of mature insulin in secretory granules

Number of insulin molecules detected	Control	GRP94i	GRP94 KO
0	68	84	78.5
1–2	22	10	15.5
3–4	9.7	5.4	5.8
5 and more	11.7	8.4	5.5

Data represent the percentage of each category of stained vesicles vs. all vesicles counted in a given experimental condition.