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. 2019 Mar 21;7:45. doi: 10.1186/s40168-019-0656-z

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Tripartite Lachnospiraceae incertae sedis subnetwork. a Demonstrates the Lachnospiracea incertae sedis healthy controls subnetwork. b Demonstrates the Lachnospiracea incertae sedis IBS subnetwork. c Demonstrates the Lachnospiracea incertae sedis difference network. Functional brain connectivity of regions of interest is presented with the region of interest noted in a larger font, with the connectivity measure and lateralization indicated below in the form X_Y, where X indicates a connectivity measure (B betweenness centrality, E eigenvector centrality, S degree strength) and Y indicates lateralization (L left, R right). Pain Thresh pain threshold during balloon distension, XIVa Clostridium XIVa, Lachnospiraceae Lachnospiraceae incertae sedis