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The Journal of Clinical Investigation logoLink to The Journal of Clinical Investigation
. 2019 Apr 1;129(4):1801. doi: 10.1172/JCI128527

DNA hypermethylation within TERT promoter upregulates TERT expression in cancer

Donghyun D Lee, Ricardo Leão, Martin Komosa, Marco Gallo, Cindy H Zhang, Tatiana Lipman, Marc Remke, Abolfazl Heidari, Nuno Miguel Nunes, Joana D Apolónio, Aryeh J Price, Ramon Andrade De Mello, João S Dias, David Huntsman, Thomas Hermanns, Peter J Wild, Robert Vanner, Gelareh Zadeh, Jason Karamchandani, Sunit Das, Michael D Taylor, Cynthia E Hawkins, Jonathan D Wasserman, Arnaldo Figueiredo, Robert J Hamilton, Mark D Minden, Khalida Wani, Bill Diplas, Hai Yan, Kenneth Aldape, Mohammad R Akbari, Arnavaz Danesh, Trevor J Pugh, Peter B Dirks, Pedro Castelo-Branco, Uri Tabori
PMCID: PMC6436876  PMID: 30932912

Original citation: J Clin Invest. 2019;129(1):223–229. https://doi.org/10.1172/JCI121303

Citation for this corrigendum: J Clin Invest. 2019;129(4):1801. https://doi.org/10.1172/JCI128527

Of the 1352 samples in the cohort, which were provided by multiple collaborators, four samples of breast tissue for which DNA was analyzed were a part of another study. Since these samples did not go through the same rigorous screening process, including pathology review and extraction of DNA from paraffin tissues, that was applied to all other samples, the authors are less confident in their exact identity and have decided to retract them from the study. This does not change the message of the paper, but results in changes in and in one pie chart in Figure 2E, that for breast cancer. The corrected figure parts are below. In addition, the supplemental material containing sample information has been updated online.

graphic file with name jci-129-128527-g231.jpg

The authors regret the error.

Version 1. 04/01/2019

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