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. Author manuscript; available in PMC: 2019 May 3.
Published in final edited form as: Leukemia. 2018 Oct 1;33(5):1135–1147. doi: 10.1038/s41375-018-0269-8

Figure 4: Microsatellite instability found in Mlh1+/+ and Mlh1+/− tumors.

Figure 4:

Stable MSI (MSI-S) was found in control tissue (Mlh1+/+) via the markers mBat-26 (A), mBat-37 (B), mBat-59 (C), and mBat-64 (D). Similarly, high MSI (MSI-H) was observed in Mlh1+/− tumor sample also via mBat-26 (E), mBat-37 (F), mBat-59 (G), and mBat-64 (H). MSI distribution in Mlh1+/+ vs Mlh1+/− tumors (I). MSI-H distribution found in tumors of irradiated Mlh1+/− mice (J). Number of Mlh1+/+ and Mlh1+/− tumors used for the analysis were 15 and 43, respectively. Distributions were tested using Chi-square tests.