Skip to main content
Deutsches Ärzteblatt International logoLink to Deutsches Ärzteblatt International
letter
. 2019 Feb 1;116(5):70. doi: 10.3238/arztebl.2019.0070b

Correspondence (letter to the editor): Evidence-Based Blood Pressure Goals

Günther Egidi *
PMCID: PMC6444037  PMID: 30950387

The recommendation to further reduce blood pressure in patients with renal insufficiency or diabetes is not evidence-based: for renal insufficiency, there is no evidence of benefit for having target values <140/90 mm Hg (1); for diabetes mellitus, it can even be harmful (2). Lowering diastolic blood pressure <80–70 mm Hg for people over 65 is not only not evidence-based—this recommendation seems downright dangerous for older people. It remains completely incomprehensible why the recommendations of the German College of General Practitioners and Family Physicians’ (DEGAM) S3 Guideline on Cardiovascular Prevention of 2017 (3), which is valid in Germany, was not mentioned in the article (4). In the Guideline, an unanimous consensus was reached for the following recommendations (as well as for others):

  • The primary goal of antihypertensive treatment is to reduce the overall cardiovascular risk. In general, the target blood pressure should be =140 mm Hg systolic and =90 mm Hg diastolic.

  • For persons over 80, the decision to start or stop therapy should be made on a case-by-case basis.

The primary selection of antihypertensives should be based on efficacy, tolerability, comorbidities, and cost.

Footnotes

Conflict of interest statement

The author declares that no conflict of interest exists.

References

  • 1.Tsai WC, Wu HY, Peng YS, et al. Association of intensive blood pressure control and kidney disease progression in nondiabetic patients with chronic kidney disease A systematic review and metaanalysis. JAMA Intern Med. 2017;177:792–799. doi: 10.1001/jamainternmed.2017.0197. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 2.Brunström M, Carlberg B. Effect of antihypertensive treatment at different blood pressure levels in patients with diabetes mellitus: systematic review and meta-analyses. BMJ. 2016 doi: 10.1136/bmj.i717. 352: i717. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 3.DEGAM-S3-Leitlinie. Hausärztliche Risikoberatung zur kardiovaskulären Prävention. www.awmf.org/leitlinien/detail/ll/053-024.html (last accessed on 2 September 2018) [Google Scholar]
  • 4.Jordan J, Kurschat C, Reuter H. Arterial hypertension—diagnosis and treatment. Dtsch Arztebl Int. 2018;115:557–568. doi: 10.3238/arztebl.2018.0557. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Deutsches Ärzteblatt International are provided here courtesy of Deutscher Arzte-Verlag GmbH

RESOURCES