FIG 1.
Fungal burden on dentures and palate tissues in rats inoculated with C. albicans and/or C. glabrata. Rats fitted with dentures were inoculated 3 times at 3-day intervals with 1 × 109 CFU C. albicans, C. glabrata, or both species together (5 × 108 CFU each). Swab samples of the palate (A) and denture (B) were collected weekly for a period of 4 weeks postinoculation. Fungal burden was assessed from overnight cultures of swab suspension fluid from the removable denture and associated palate tissue. Figures represent cumulative results from 2 independent experiments with 2 to 5 animals per group. Data were analyzed using repeated measures ANOVA (longitudinal data for each group) and one-way ANOVA (individual time points between groups) followed by the unpaired Student’s t test (experimental versus control groups at individual time points).