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Daily alcohol and water intake (mL) of saline- or CFA-treated C57BL/6J mice over a 3-week continuous access regimen. Pain-related consumption of fluids was assessed for (A) males (n = 8) and (B) females (n = 8) in 20 consecutive sessions. (C) Averages of daily intake were compared between saline- and CFA-treated males and females. Data are mean fluid intake ± SEM. *, **, and *** correspond to p < 0.05, p < 0.005, and p < 0.0005 difference between groups.
