Figure 6.

GPs unmask cryptic variation in parallel signaling pathways and subpathways. (a) Loci that interact with GPa influence FLO11 regulation by the Ras pathway. (b) GPb uncovers loci that primarily act through a different Ras subpathway involving Mds3, Srv2, and Tpk3. (c) Loci interacting with GPc function in a number of different pathways that are capable of regulating FLO11 activity. The locations of transcription factor-binding sites are not intended to reflect specific positioning along the FLO11 promoter. GPs, genetic perturbations.