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Postmus 2000
| Methods | RCT enrolled: 134 evaluated: 120 | |
| Participants | Inclusion: 1. metastatic small cell lung cancer 2. brain metastases (CT) 3. extracranial tumour 4. no previous treatment with chemotherapy or radiation for brain metastases 5. no prior teniposide 6. age less than 76 years Exclusion: 1. uncontrolled infection 2. serious non‐malignant disease | |
| Interventions | teniposide chemotherapy with or without WBRT | |
| Outcomes | 1. Survival 2. Time to progression 3. Duration of response | |
| Notes | QS =1 | |
