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. 2019 Jan 23;44(6):1093–1102. doi: 10.1038/s41386-019-0323-x

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — The expression of the CALCR gene in NAc is lower in high alcohol-consuming rats, whereas the expression of RAMP1 is higher in the same brain area. a The expression of CALCR in NAc is decreased in high (N = 19) compared to low alcohol-consuming (N = 25) rats. Conversely, b the expression of RAMP1 in the same area is higher in high compared to low alcohol-consuming rats. (Data are presented as mean ± SEM of the ΔC_T values; ⁺P < 0.05)