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Blood brain barrier (BBB) penetration analysis with a lazar tool prediction for top five therapeutic ligands involved in p-tau inhibition.
| S. No | Compound | Structure | Blood Brain Barrier Penetration (Human) Prediction | Probability Penetrating | Probability Non-Penetrating |
|---|---|---|---|---|---|
| 1 | Ligand 1 |
|
Penetrating | 0.0944 | 0.0722 |
| 2 | Ligand 2 |
|
Penetrating | 0.15 | 0.0667 |
| 3 | Ligand 3 |
|
Penetrating | 0.157 | 0.0933 |
| 4 | Ligand 4 |
|
Penetrating | 0.137 | 0.0738 |
| 5 | Ligand 5 |
|
Penetrating | 0.141 | 0.0539 |
