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. 2019 Apr 17;8:e44964. doi: 10.7554/eLife.44964

Figure 7. UBC dendritic brush size relates to source of input and not ON or OFF UBC subtype.

Figure 7.

(A) 3D rendering of primary afferent showing characteristic thick axon (green). Biocytin fill- gray, contact between mossy fiber and UBC- red. (B) 3D rendering of secondary mossy fiber showing thin axons and rosette-like ending. Biocytin fill- gray, contact between mossy and UBC- yellow. (C) The contact areas between recovered primary afferents and UBC brushes was smaller than those of secondary mossy fibers (t-test, p=0.0003, n = 17). (D) The surface area of the UBC brushes that received primary afferents were smaller than those of secondary mossy fiber-receiving UBCs (t-test, p=0.009, n = 18). The volume of the UBC brushes that received primary afferents were also larger than those of secondary mossy fiber-receiving UBCs (t-test, p=0.014, n = 18), not shown. (E) The volume of the somas of UBCs that received primary afferents were smaller than those of secondary mossy fiber-receiving UBCs (t-test, p=0.035, n = 15).