Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Mar 23;24(6):1154. doi: 10.3390/molecules24061154

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Scheme 1 — Reagents and conditions: (a) R₁X, NaH, DMF, 0 °C–r.t., 29–30%; (b) R₂COCl, TEA, CH₂Cl₂, 0 °C–r.t., 35–52%; (c) R₃SO₂Cl, TEA, CH₂Cl₂, 0 °C–r.t., 33–50%; (d) N-(3-bromopropyl)phthalimide, NaH, DMF, 0 °C–r.t., 50%; (e) H₂NNH₂·H₂O, EtOH, overnight, 90%; (f) R₄COCl, TEA, CH₂Cl₂, 0 °C–r.t., 22–71%; (g) R₅SO₂Cl, TEA, CH₂Cl₂, 0 °C–r.t., 21–52%.