Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Proposed molecular mechanism for the induction of DCM in αMHC-cre mice. The decrease in p38 activity enhanced JNK, resulting in an upregulation of the p53/Bax causing myocyte death. The change in p38 activity due to cre-induced DNA damage and external signaling initiated a cascade that eventually resulted in DCM.
